Botha was born in Pretoria in 1974. He graduated from the University of Pretoria with a BA (Visual Art) in 1996. He lives in Cape Town.

He has received a number of prestigious awards, including the Helgaard Steyn Prize for sculpture in 2013, the Standard Bank Young Artist Award in 2005, and the first Tollman Award in 2003. Recent solo exhibitions have taken place at the 21c Museum Hotel in Louisville (2020); North Carolina Museum of Art in Raleigh, and the 21c Museum Hotel in Durham (2019); the Norval Foundation (2018); Galerie Hans Mayer (2017); Feldbusch Wiesner Rudolph (2017, 2019, 2021); Fondation Blachère in Apt, France (2016); Galerie Jette Rudolph, Berlin (2015); the National Arts Festival in Grahamstown (2014); Kunstraum Innsbruck, Austria (2013), and the Sasol Art Museum, Stellenbosch, as the Stellenbosch University Wordfest Artist for 2013.

Notable group exhibitions include Sculpture at the Institute of Contemporary Art Indian Ocean (2018); The Divine Comedy: Heaven, purgatory and hell revisited by contemporary African artists at MMK (Museum für Moderne Kunst), Frankfurt, Germany, travelling to other venues (2014-5); Lichtspiele at Museum Biedermann, Donaueschingen, Germany (2014); Imaginary Fact: South African Art and the Archive, the South African Pavilion at the 55th Venice Biennale (2013); The Rainbow Nation, Museum Beelden aan Zee, The Hague (2012); the Göteborg Biennial, Sweden (2011); Memories of the Future: The Olbricht Collection, La Maison Rouge, Paris (2011); the 11th Triennale für Kleinplastik, Fellbach, Germany (2010); Peekaboo: Current South Africa, Tennis Palace Art Museum, Helsinki (2010); Olvida Quien Soy - Erase me from who I am, Centro Atlantico de Arte Moderno, Las Palmas de Gran Canaria (2006); the seventh edition of Dak'Art, the Dakar Biennale (2006); and the touring exhibition Africa Remix (2004-2007).